Chemical modification of potassium channel gating in frog myelinated nerve by trinitrobenzene sulphonic acid.
نویسندگان
چکیده
منابع مشابه
Potassium Channels in Myelinated Nerve
The permeability of K channels to various cations is studied in myelinated nerve. Ionic currents under voltage clamp are measured in Ringer solution containing tetrodotoxin and a high concentration of the test ion. Reversal potentials for current in K channels are determined and used with the Goldman-Hodgkin-Katz equation to calculate relative permeabilities. The ratios P(Tl):P(K):P(Rb):P(NHNH4...
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The properties of voltage-dependent Na channels modified by veratridine (VTD) were studied in voltage-clamped nodes of Ranvier of the frog Rana pipiens. Two modes of gating of VTD-modified channels are described. The first, occurring on a time scale of milliseconds, is shown to be the transition of channels between a modified resting state and a modified open state. There are important qualitat...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1983
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1983.sp014843